Papers (links point to pdf files)

• Juers, D.H., Lovelace, J., Bellamy, H.D., Snell, E.H., Matthews, B.W. and Borgstahl, G.E.O. (2007) Changes to Crystals of E. coli b-galactosidase During Room-Temperature Low-Temperature Cycling and Their Relation to Cryo-Annealing. Acta Crystallographica D63, 1139-1153.
• Juers, DH , Kim J, Sieburth, S McN, and Matthews, BW. (2005) Structural Analysis of Silendiols as Transition-State-Analogue Inhibitors of the Benchmark Metalloprotease Thermolysin. Biochemistry 44: 16524-16528.
• Juers, DH and Matthews, BW. (2004) Cryo-cooling in macromolecular crystallography: advantages, disadvantages and optimization. Quarterly Reviews of Biophysics 37, 2 pp. 1-15.
• Juers, DH and Matthews, BW. (2004) The Role of Solvent Transport in Macromolecular Crystal Annealing. Acta Crystallographica, D60, 412-421.
• Juers, DH, Hakda, S, Matthews, B, Huber, G. (2003) Structural Basis for the Altered Activity of Gly794 Variants of E. coli b -galactosidase. Biochemistry 42: 13505-13511.
• Shoemaker, GK, Juers, DH, Coombs, JML, Matthews, BW and Craig, DB. (2003) Microheterogeneity in Enzyme Crystals. Biochemistry 42: 1707-1710.
• Juers DH, Heightman TD, Vasella A, McCarter, JD, Mackenzie L, Withers SG and Matthews BW.   (2001) A Structural View of the Action of E. coli (lac Z) b -Galactosidase. Biochemistry 40 : 14781-14794.
• Juers DH and Matthews BW. (2001) Reversible Lattice Repacking Illustrates the Temperature Dependence of Macromolecular Interactions. Journal of Molecular Biology 311 851-862.
• Juers DH , Jacobson RH, Wigley D, Zhang XJ, Huber RE, Tronrud DE and Matthews BW. (2000) High resolution refinement of b -galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for a -complementation. Protein Science 9 : 1685-1699.
• Juers DH , Huber RE and Matthews BW. (1999) Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between b -galactosidase and other glycohydrolases. Protein Science 8 :122-136.
• Holland DR, Hausrath AC, Juers DH and Matthews BW. (1995) Structural analysis of zinc substitutions in the active site of thermolysin. Protein Science 4 : 1955-1965.

Dissertation: A Structural View of Beta-Galactosidase in Action (2000)

Talks and Presentations

• The Role of Cryoprotectants in Cryo-Cooling and Annealing. Poster. Annual Meeting of the Biophysical Society, Long Beach, CA, Feb 2005. Lecture. Northwest Crystallography Workshop, Seattle, WA, June 2004.
• The Role of Water Transport in Cryo-Annealing. Lecture. Annual Meeting of the American Crystallographic Association, Cincinnati, OH June 2003.
• The Role of Solvent Transport in Annealing. Lecture. 7 th Northwest Crystallography Workshop, Vancouver, BC, June 2002.
• Temperature Dependent Structural Changes in Frozen Crystals of beta-Galactosidase. Poster. 45th Annual Meeting of the Biophysical Society, Boston MA, Feb 2001. The 15th West Coast Protein Crystallography Workshop, Asilomar CA, Mar 2001.
• Reversible Changes in E. coli (lac Z) beta-Galactosidase Crystal Packing with Freezing. Lecture. 6th Northwest Crystallography Workshop, Eugene OR, July 2000.
• Structural Enzymology of E. coli beta-Galactosidase: The Role of a Ligand-Induced Switch in the Dual Activity of the Enzyme. Poster. The 14th West Coast Protein Crystallography Workshop, Asilomar CA, March 1999.
• High Resolution Structures of beta-Galactosidase Inhibitor Complexes. Poster. 12th Symposium of the Protein Society, San Diego CA, July 1998.
• Structural Studies Directed Towards the Mechanism of Action of beta-Galactosidase. Poster. 11th Symposium of the Protein Society, Boston MA, July 1997.
• Engineering by Nature and Why beta-Galactosidase is So Big. Lecture. 4th Northwest Crystallography Workshop, Eugene OR, June 1996.
• A Structural Basis for the Activity of beta-Galactosidase. Lecture. 12th West Coast Protein Crystallography Workshop, Asilomar CA, March 1995.